BDBM242754 US10030025, Compound 18::US10836768, Cpd no 18::US11731974, Compound 18::US9422299, 18::US9987274, Compound 18

SMILES C[C@H]1N(CCn2c1nnc2-c1nc(C)ns1)C(=O)c1ccc(F)cc1F

InChI Key InChIKey=OZEMPZBRQPJERB-MRVPVSSYSA-N

Data  16 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 242754   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Euroscreen

US Patent
LigandPNGBDBM242754(US10030025, Compound 18 | US10836768, Cpd no 18 | ...)
Affinity DataIC50:  7.00E+4nMAssay Description:The hERG inhibition study aims at quantifying the in vitro effects of compounds of the invention on the potassium-selective IKr current generated in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Euroscreen

US Patent
LigandPNGBDBM242754(US10030025, Compound 18 | US10836768, Cpd no 18 | ...)
Affinity DataIC50:  7.00E+4nMAssay Description:The human ether-a-go-go related gene (hERG) encodes the inward rectifying voltage gated potassium channel in the heart (Igr) which is involved in car...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Euroscreen

US Patent
LigandPNGBDBM242754(US10030025, Compound 18 | US10836768, Cpd no 18 | ...)
Affinity DataIC50:  7.00E+4nMAssay Description:The human ether-a-go-go related gene (hERG) encodes the inward rectifying voltage gated potassium channel in the heart (IKr) which is involved in car...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent